Citrobacter freundii is an opportunistic microbe, and often causes major opportunistic infections, i.e. the bacterium does not produce any disease-symptoms in healthy humans; it only afflicts those who have a weak and debilitated immune system. People who have a weakened immune system tend to develop infections of the urinary tract, respiratory tract, and the blood. Pancreatic, hepatic, and biliary diseases are also commonly caused by C. freundii.
Citrobacter Freundii Infections Symptoms
• Urinary tract infections caused by Citrobacter freundii trigger: a burning sensation during urination, increased urge to urinate, offensive smelling urine, scanty urination, blood in the urine, fever, and burning or pain in the lower back and / or pelvis. The most significant cause for C. freundii infection is wiping back to front after passing motions and poor hygiene levels after sexual intercourse.
• C. freundii is also known to cause abnormal inflammatory changes in the intestine, sometimes even resulting in necrotic changes.
• Citrobacter freundii has been linked to neonatal meningitis as well. The meninges or coverings of the brain get inflamed due to bacterial infiltration. C. freundii has the capacity to break through the blood-brain barrier (comprising of the brain capillary endothelium and the choroid plexus epithelium). It can invade and replicate in the brain too. Common clinical features and citrobacter freundii symptoms include: high grade fever, projectile vomiting and seizures.
• Peritonitis and tunnel infection due to Citrobacter freundii have also been reported. This has most frequently been seen in hospitalized and immune-compromised patients who have been kept on a urinary catheter.